I'm generally not a big fan of the vanity wall of publications concept, which is just another place to maintain; the best place to look for publications is at one of the providers below. But I figured out how to auto-populate this publication list from my bibtex database using JabRef, so it's no more work to have a list here, so here it is.



    List of publications on Pubmed | Google Scholar | ORCID.
  1. Dozmorov MG, Tyc KM, Sheffield NC, Boyd DC, Olex AL, Reed J, and Harrell JC.
    Chromatin conformation capture (Hi-C) sequencing of patient-derived xenografts: analysis guidelines
    GigaScience (2021) DOI: /10.1093/gigascience/giab022
  2. Sheffield NC, Stolarczyk M, Reuter VP, and Rendeiro A.
    Linking big biomedical datasets to modular analysis with Portable Encapsulated Projects
    bioRxiv (2021) DOI: 10.1101/2020.10.08.331322
  3. Gharavi E, Gu A, Zheng G, Smith JP, Zhang A, Brown DE, and Sheffield NC.
    Embeddings of genomic region sets capture rich biological associations in low dimensions
    Bioinformatics (2021) DOI: 10.1093/bioinformatics/btab439
  4. Stolarczyk M, Xue B, and Sheffield NC.
    Identity and compatibility of reference genome resources
    NAR Genomics and Bioinformatics (2021) DOI: 10.1093/nargab/lqab036
  5. Yates AD, Adams J, Chaturvedi S, Davies R, Laird M, Leinonen R, Nag R, Sheffield NC, Hofmann O, and Keane T.
    Refget: standardised access to reference sequences
    Bioinformatics (2021) DOI: 10.1093/bioinformatics/btab524
  6. Gu A, Cho HJ, and Sheffield NC.
    Bedshift: perturbation of genomic interval sets
    Genome Biology (2021) DOI: 10.1186/s13059-021-02440-w
  7. Manjegowda MC, Joy-Gaba J, Wengert E, Saga AU, Warthen D, Kuchler A, Gaykema R, Patel MK, Sheffield NC, and Scott MM.
    DNA Methyltransferase 1 and 3a Expression in the Frontal Cortex Regulates Palatable Food Consumption
    bioRxiv (2021) DOI: 10.1101/2021.05.23.445176
  8. Peneder P, Stütz AM, Surdez D, Krumbholz M, Semper S, Chicard M, Sheffield NC, Pierron G, Lapouble E, Tötzl M, Ergüner B, Barreca D, Rendeiro AF, Agaimy A, Boztug H, Engstler G, Dworzak M, Bernkopf M, Taschner-Mandl S, Ambros IM, Myklebost O, Marec-Bérard P, Burchill SA, Brennan B, Strauss SJ, Whelan J, Schleiermacher G, Schaefer C, Dirksen U, Hutter C, Boye K, Ambros PF, Delattre O, Metzler M, Bock C, and Tomazou EM.
    Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden
    Nature Communications (2021) DOI: 10.1038/s41467-021-23445-w
  9. Smith JP, Dutta AB, Sathyan KM, Guertin MJ, and Sheffield NC.
    PEPPRO: quality control and processing of nascent RNA profiling data
    Genome Biology (2021) DOI: 10.1186/s13059-021-02349-4
  10. Feng J, and Sheffield NC.
    IGD: high-performance search for large-scale genomic interval datasets
    Bioinformatics (2020) DOI: 10.1093/bioinformatics/btaa1062
  11. Smith JP, Corces R, Xu J, Wei Y, Reuter VP, Chang HY, and Sheffield NC.
    PEPATAC: An optimized ATAC-seq pipeline with serial alignments
    bioRxiv (2020) DOI: 10.1101/2020.10.21.347054
  12. VijayKrishna N, Joshi J, Coraor N, Hillman-Jackson J, Bouvier D, van den Beek M, Eguinoa I, Coppens F, Golitsynskiy S, Stolarczyk M, Sheffield NC, Gladman S, Cuccuru G, Grüning B, Soranzo N, Rasche H, Langhorst BW, Bernt M, Fornika D, de Lima Morais DA, Barrette M, van Heusden P, Petrillo M, Puertas-Gallardo A, Patak A, Hotz H-R, and Blankenberg D.
    Expanding the Galaxy's reference data
    bioRxiv (2020) DOI: 10.1101/2020.10.09.327114
  13. Lawson JT, Smith JP, Bekiranov S, Garrett-Bakelman FE, and Sheffield NC.
    COCOA: coordinate covariation analysis of epigenetic heterogeneity
    Genome Biology (2020) DOI: 10.1186/s13059-020-02139-4
  14. Sienkiewicz K, Chen J, Chatrath A, Lawson JT, Sheffield NC, Zhang L, and Ratan A.
    Data Integration with SUMO Detects Latent Relationships Between Patients in Lower-Grade Gliomas
    bioRxiv (2020) DOI: 10.1101/2020.08.10.244343
  15. Smith JP, and Sheffield NC.
    Analytical Approaches for ATAC-seq Data Analysis
    Current Protocols in Human Genetics (2020) DOI: 10.1002/cphg.101
  16. Feng SC, Sheffield NC, and Feng J.
    Seqpare: a self-consistent metric of similarity between genomic interval sets
    F1000Research (2020) DOI: 10.1101/2020.04.05.026732
  17. Stolarczyk M, Reuter VP, Smith JP, Magee NE, and Sheffield NC.
    Refgenie: a reference genome resource manager
    GigaScience (2020) DOI: 10.1093/gigascience/giz149
  18. Sheffield NC.
    Bulker: a multi-container environment manager
    OSF Preprints (2019) DOI: 10.31219/osf.io/natsj
  19. Feng J, Ratan A, and Sheffield NC.
    Augmented Interval List: a novel data structure for efficient genomic interval search
    Bioinformatics (2019) DOI: 10.1093/bioinformatics/btz407
  20. Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, Felau I, Castro MAA, Berman BP, Staudt LM, Zenklusen JC, Laird PW, Curtis C, Greenleaf WJ, and Chang HY.
    The chromatin accessibility landscape of primary human cancers
    Science (2018) DOI: 10.1126/science.aav1898
  21. Klughammer J, Kiesel B, Roetzer T, Fortelny N, Nemc A, Nenning K-H, Furtner J, Sheffield NC, Datlinger P, Peter N, Nowosielski M, Augustin M, Mischkulnig M, Ströbel T, Alpar D, Ergüner B, Senekowitsch M, Moser P, Freyschlag CF, Kerschbaumer J, Thome C, Grams AE, Stockhammer G, Kitzwoegerer M, Oberndorfer S, Marhold F, Weis S, Trenkler J, Buchroithner J, Pichler J, Haybaeck J, Krassnig S, Ali KM, von Campe G, Payer F, Sherif C, Preiser J, Hauser T, Winkler PA, Kleindienst W, Würtz F, Brandner-Kokalj T, Stultschnig M, Schweiger S, Dieckmann K, Preusser M, Langs G, Baumann B, Knosp E, Widhalm G, Marosi C, Hainfellner JA, Woehrer A, and Bock C.
    The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
    Nature Medicine (2018) DOI: 10.1038/s41591-018-0156-x
  22. Simovski B, Kanduri C, Gundersen S, Titov D, Domanska D, Bock C, Bossini-Castillo L, Chikina M, Favorov A, Layer RM, Mironov AA, Quinlan AR, Sheffield NC, Trynka G, and Sandve GK.
    Coloc-stats: a unified web interface to perform colocalization analysis of genomic features
    Nucleic Acids Research (2018) DOI: 10.1093/nar/gky474
  23. Lawson J, Tomazou E, Bock C, and Sheffield NC.
    MIRA: An R package for DNA methylation-based inference of regulatory activity
    Bioinformatics (2018) DOI: 10.1093/bioinformatics/bty083
  24. Wang Z, Civelek M, Miller CL, Sheffield NC, Guertin MJ, and Zang C.
    BART: a transcription factor prediction tool with query gene sets or epigenomic profiles
    Bioinformatics (2018) DOI: 10.1093/bioinformatics/bty194
  25. Sheffield NC, Nagraj V, and Reuter VP.
    simpleCache: R caching for reproducible, distributed, large-scale projects
    The Journal of Open Source Software (2018) DOI: 10.21105/joss.00463
  26. Nagraj V, Magee N, and Sheffield NC.
    LOLAweb: a containerized web server for interactive genomic locus overlap enrichment analysis
    Nucleic Acids Research (2018) DOI: 10.1093/nar/gky464
  27. Litzenburger UM, Buenrostro JD, Wu B, Shen Y, Sheffield NC, Kathiria A, Greenleaf WJ, and Chang HY.
    Single-cell epigenomic variability reveals functional cancer heterogeneity
    Genome Biol (2017) DOI: 10.1186/s13059-016-1133-7
  28. Sheffield NC, Pierron G, Klughammer J, Datlinger P, Schönegger A, Schuster M, Hadler J, Surdez D, Guillemot D, Lapouble E, Freneaux P, Champigneulle J, Bouvier R, Walder D, Ambros IM, Hutter C, Sorz E, Amaral AT, de Alava E, Schallmoser K, Strunk D, Rinner B, Liegl-Atzwanger B, Huppertz B, Leithner A, de Pinieux G, Terrier P, Laurence V, Michon J, Ladenstein R, Holter W, Windhager R, Dirksen U, Ambros PF, Delattre O, Kovar H, Bock C, and Tomazou EM.
    DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma
    Nature Medicine (2017) DOI: 10.1038/nm.4273
  29. Sheffield NC, and Bock C.
    LOLA: enrichment analysis for genomic region sets and regulatory elements in R and Bioconductor
    Bioinformatics (2016) DOI: 10.1093/bioinformatics/btv612
  30. Bock C, Farlik M, and Sheffield NC.
    Multi-Omics of Single Cells: Strategies and Applications
    Trends Biotechnol (2016) DOI: 10.1016/j.tibtech.2016.04.004
  31. Kovar H, Amatruda J, Brunet E, Burdach S, Cidre-Aranaz F, de Alva E, Dirksen U, van der Ent W, Grohar P, Grunewald TG, Helman L, Houghton P, Iljin K, Korsching E, Ladanyi M, Lawlor E, Lessnick S, Ludwig J, Meltzer P, Metzler M, Mora J, Moriggl R, Nakamura T, Papamarkou T, Sarikas BR, Redini F, Richter GH, Rossig C, Schadler K, Schafer BW, Scotlandi K, Sheffield NC, Shelat A, Snaar-Jagalska E, Sorensen P, Stegmaier K, Stewart E, Sweet-Cordero A, Szuhai K, Tirado OM, Tirode F, Toretsky J, Tsafou K, Uren A, Zinovyev A, and Delattre O.
    The second European interdisciplinary Ewing sarcoma research summit – A joint effort to deconstructing the multiple layers of a complex disease
    Oncotarget (2016) DOI: 10.18632/oncotarget.6937
  32. Klughammer J, Datlinger P, Printz D, Sheffield NC, Farlik M, Hadler J, Fritsch G, and Bock C.
    Differential DNA Methylation Analysis without a Reference Genome
    Cell Reports (2015) DOI: 10.1016/j.celrep.2015.11.024
  33. Schmidl C, Rendeiro AF, Sheffield NC, and Bock C.
    ChIPmentation: fast, robust, low-input ChIP-seq for histones and transcription factors
    Nat. Methods (2015) DOI: 10.1038/nmeth.3542
  34. Farlik M, Sheffield NC, Nuzzo A, Datlinger P, Schonegger A, Klughammer J, and Bock C.
    Single-cell DNA methylome sequencing and bioinformatic inference of epigenomic cell-state dynamics
    Cell Reports (2015) DOI: 10.1016/j.celrep.2015.02.001
  35. Tomazou EM, Sheffield NC, Schmidl C, Schuster M, Schonegger A, Datlinger P, Kubicek S, Bock C, and Kovar H.
    Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1
    Cell Reports (2015) DOI: 10.1016/j.celrep.2015.01.042
  36. Sheffield NC, Thurman RE, Song L, Safi A, Stamatoyannopoulos JA, Lenhard B, Crawford GE, and Furey TS.
    Patterns of regulatory activity across diverse human cell-types predict tissue identity, transcription factor binding, and long-range interactions
    Genome Res (2013) DOI: 10.1101/gr.152140.112
  37. Sheffield NC.
    The Interaction between Base Compositional Heterogeneity and Among-Site Rate Variation in Models of Molecular Evolution
    ISRN Evolutionary Biology (2013) DOI: 10.5402/2013/391561
  38. Tewari AK, Yardimci GG, Shibata Y, Sheffield NC, Song L, Taylor BS, Georgiev SG, Coetzee GA, Ohler U, Furey TS, Crawford GE, and Febbo PG.
    Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity
    Genome Biol (2012) DOI: 10.1186/gb-2012-13-10-r88
  39. ENCODE Consortium.
    An integrated encyclopedia of DNA elements in the human genome
    Nature (2012) DOI: 10.1038/nature11247
  40. Natarajan A, Yardimci GG, Sheffield NC, Crawford GE, and Ohler U.
    Predicting cell-type-specific gene expression from regions of open chromatin
    Genome Res (2012) DOI: 10.1101/gr.135129.111
  41. Thurman RE, Rynes E, Humbert R, Vierstra J, Matthew T, Haugen E, Sheffield NC, Stergachis AB, Wang H, Vernot B, Garg K, Sandstrom R, Bates D, Canfield TK, Diegel M, Dunn D, Ebersol AK, Frum T, Giste E, Johnson AK, Johnson EM, Kutyavin T, Lajoie B, Lee K, Lee K, London D, Lotakis D, Neph S, Neri F, Nguyen D, Reynolds AP, Roach V, Safi A, Sanchez ME, Sanyal A, Shafer A, Simon JM, Song L, Vong S, Weaver M, Zhang Z, Zhang Z, Lenhard B, Tewari M, Dorschner MO, Hansen RS, Navas PA, Iyer VR, Lieb JD, and Sunyaev SR.
    The accessible chromatin landscape of the human genome
    Nature (2012) DOI: 10.1038/nature11232
  42. Shibata Y, Sheffield NC, Fedrigo O, Babbitt CC, Wortham M, Tewari AK, London D, Song L, Lee B-K, Iyer VR, Parker SCJ, Margulies EH, Wray GA, Furey TS, and Crawford GE.
    Extensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection
    PLos Genet (2012) DOI: 10.1371/journal.pgen.1002789
  43. Sheffield NC, and Furey TS.
    Identifying and characterizing regulatory sequences in the human genome with chromatin accessibility assays
    Genes (2012) DOI: 10.3390/genes3040651
  44. Song L, Zhang ZZ, Grasfeder LL, Boyle AP, Giresi PG, Lee B-K, Sheffield NC, Graf S, Huss M, Keefe D, Liu Z, London D, McDaniell RM, Shibata Y, Showers KA, Simon JM, Vales T, Wang T, Winter D, Clarke ND, Birney E, Iyer VR, Crawford GE, Lieb JD, and Furey TS.
    Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
    Genome Res (2011) DOI: 10.1101/gr.121541.111
  45. Myers RM, Stamatoyannopoulos J, Snyder M, Dunham I, Hardison RC, Bernstein BE, Gingeras TR, Kent WJ, Birney E, Wold B, Crawford GE, Encode T, and Consortium P.
    A user's guide to the encyclopedia of DNA elements (ENCODE)
    PLoS Biol (2011) DOI: 10.1371/journal.pbio.1001046
  46. Sheffield NC, Hiatt KD, Valentine MC, Song H, and Whiting MF.
    Mitochondrial genomics in Orthoptera using MOSAS
    Mitochondrial DNA (2010) DOI: 10.3109/19401736.2010.500812
  47. Song H, Sheffield NC, Cameron SL, Miller KB, and Whiting MF.
    When phylogenetic assumptions are violated: base compositional heterogeneity and among-site rate variation in beetle mitochondrial phylogenomics
    Syst. Entomol (2010) DOI: 10.1111/j.1365-3113.2009.00517.x
  48. Sheffield NC, Song H, Cameron SL, and Whiting MF.
    Nonstationary evolution and compositional heterogeneity in beetle mitochondrial phylogenomics
    Syst. Biol (2009) DOI: 10.1093/sysbio/syp037
  49. Sheffield NC, Song H, Cameron SL, and Whiting MF.
    A comparative analysis of mitochondrial genomes in Coleoptera (Arthropoda: Insecta) and genome descriptions of six new beetles
    Mol. Biol. Evol (2008) DOI: 10.1093/molbev/msn198
  50. Stacey A, Sheffield NC, and Crandall KA.
    Calculating expected DNA remnants from ancient founding events in human population genetics
    BMC Genet (2008) DOI: 10.1186/1471-2156-9-66